Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
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Author / Creator
Braun, Fabian , Abed, Ahmed , Sellung, Dominik , Rogg, Manuel , Woidy, Mathias , Eikrem, Oysten , Wanner, Nicola , Gambardella, Jessica , Laufer, Sandra D. , Haas, Fabian , Wong, Milagros N. , Dumoulin, Bernhard , Rischke, Paula , Mühlig, Anne , Sachs, Wiebke , von Cossel, Katharina , Schulz, Kristina , Muschol, Nicole , Gersting, Sören W. , Muntau, Ania C. , Kretz, Oliver , Hahn, Oliver , Rinschen, Markus M. , Mauer, Michael , Bork, Tillmann , Grahammer, Florian , Liang, Wei , Eierhoff, Thorsten , Römer, Winfried , Hansen, Arne , Meyer-Schwesinger, Catherine , Iaccarino, Guido , Tøndel, Camilla , Marti, Hans-Peter , Najafian, Behzad , Puelles, Victor G. , Schell, Christoph and Huber, Tobias B.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Current therapies for Fabry disease are based on reversing intracellular accumulation of globotriaosylceramide (Gb3) by enzyme replacement therapy (ERT) or chaperone-mediated stabilization of the defective enzyme, thereby alleviating lysosomal dysfunction. However, their effect in the reversal of end-organ damage, like kidney injury and chronic kid...
Alternative Titles
Full title
Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
Authors, Artists and Contributors
Author / Creator
Abed, Ahmed
Sellung, Dominik
Rogg, Manuel
Woidy, Mathias
Eikrem, Oysten
Wanner, Nicola
Gambardella, Jessica
Laufer, Sandra D.
Haas, Fabian
Wong, Milagros N.
Dumoulin, Bernhard
Rischke, Paula
Mühlig, Anne
Sachs, Wiebke
von Cossel, Katharina
Schulz, Kristina
Muschol, Nicole
Gersting, Sören W.
Muntau, Ania C.
Kretz, Oliver
Hahn, Oliver
Rinschen, Markus M.
Mauer, Michael
Bork, Tillmann
Grahammer, Florian
Liang, Wei
Eierhoff, Thorsten
Römer, Winfried
Hansen, Arne
Meyer-Schwesinger, Catherine
Iaccarino, Guido
Tøndel, Camilla
Marti, Hans-Peter
Najafian, Behzad
Puelles, Victor G.
Schell, Christoph
Huber, Tobias B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232004
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232004
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI157782
