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Uridine-derived ribose fuels glucose-restricted pancreatic cancer

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Uridine-derived ribose fuels glucose-restricted pancreatic cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232363

Uridine-derived ribose fuels glucose-restricted pancreatic cancer

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Publication information

Publisher

London: Nature Publishing Group UK

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Contents

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease notoriously resistant to therapy
1
,
2
. This is mediated in part by a complex tumour microenvironment
3
, low vascularity
4
, and metabolic aberrations
5
,
6
. Although altered metabolism drives tumour progression, the spectrum of metabolites used as nut...

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Full title

Uridine-derived ribose fuels glucose-restricted pancreatic cancer

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232363

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232363

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ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06073-w

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