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Translation of circHGF RNA encodes an HGF protein variant promoting glioblastoma growth through stim...

Translation of circHGF RNA encodes an HGF protein variant promoting glioblastoma growth through stim...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232650

Translation of circHGF RNA encodes an HGF protein variant promoting glioblastoma growth through stimulation of c-MET

About this item

Full title

Translation of circHGF RNA encodes an HGF protein variant promoting glioblastoma growth through stimulation of c-MET

Publisher

New York: Springer US

Journal title

Journal of neuro-oncology, 2023-05, Vol.163 (1), p.207-218

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Introduction
HGF/c-MET signaling is a significant driver of glioblastoma (GBM) growth and disease progression. Unfortunately, c-MET targeted therapies have been found to be largely ineffective suggesting additional redundant mechanisms of c-MET activation.
Methods
Utilizing RNA-sequencing (RNA-seq) and ribosome profiling analyses of circul...

Alternative Titles

Full title

Translation of circHGF RNA encodes an HGF protein variant promoting glioblastoma growth through stimulation of c-MET

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232650

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10232650

Other Identifiers

ISSN

0167-594X

E-ISSN

1573-7373

DOI

10.1007/s11060-023-04331-5

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