The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway
The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway
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Author / Creator
Liang, Xue , Yao, Jiping , Cui, Danrui , Zheng, Weiyang , Liu, Yanning , Lou, Guohua , Ye, Bingjue , Shui, Liyan , Sun, Yi , Zhao, Yongchao and Zheng, Min
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
TRAF2 (Tumor necrosis factor receptor-associated factor 2) is a dual function protein, acting as an adaptor protein and a ubiquitin E3 ligase, which plays an essential role in mediating the TNFα-NFκB signal pathway. Dysregulated expression of TRAF2 has been reported in a variety of human cancers. Whether and how TRAF2 regulates the growth of liver...
Alternative Titles
Full title
The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10244464
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10244464
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-023-01164-7
