Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse m...
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model
About this item
Full title
Author / Creator
Waugh, Katherine A. , Minter, Ross , Baxter, Jessica , Chi, Congwu , Galbraith, Matthew D. , Tuttle, Kathryn D. , Eduthan, Neetha P. , Kinning, Kohl T. , Andrysik, Zdenek , Araya, Paula , Dougherty, Hannah , Dunn, Lauren N. , Ludwig, Michael , Schade, Kyndal A. , Tracy, Dayna , Smith, Keith P. , Granrath, Ross E. , Busquet, Nicolas , Khanal, Santosh , Anderson, Ryan D. , Cox, Liza L. , Estrada, Belinda Enriquez , Rachubinski, Angela L. , Lyford, Hannah R. , Britton, Eleanor C. , Fantauzzo, Katherine A. , Orlicky, David J. , Matsuda, Jennifer L. , Song, Kunhua , Cox, Timothy C. , Sullivan, Kelly D. and Espinosa, Joaquin M.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Down syndrome (DS), the genetic condition caused by trisomy 21, is characterized by variable cognitive impairment, immune dysregulation, dysmorphogenesis and increased prevalence of diverse co-occurring conditions. The mechanisms by which trisomy 21 causes these effects remain largely unknown. We demonstrate that triplication of the interferon rece...
Alternative Titles
Full title
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model
Authors, Artists and Contributors
Author / Creator
Minter, Ross
Baxter, Jessica
Chi, Congwu
Galbraith, Matthew D.
Tuttle, Kathryn D.
Eduthan, Neetha P.
Kinning, Kohl T.
Andrysik, Zdenek
Araya, Paula
Dougherty, Hannah
Dunn, Lauren N.
Ludwig, Michael
Schade, Kyndal A.
Tracy, Dayna
Smith, Keith P.
Granrath, Ross E.
Busquet, Nicolas
Khanal, Santosh
Anderson, Ryan D.
Cox, Liza L.
Estrada, Belinda Enriquez
Rachubinski, Angela L.
Lyford, Hannah R.
Britton, Eleanor C.
Fantauzzo, Katherine A.
Orlicky, David J.
Matsuda, Jennifer L.
Song, Kunhua
Cox, Timothy C.
Sullivan, Kelly D.
Espinosa, Joaquin M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10260402
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10260402
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-023-01399-7
