Polygenic scoring accuracy varies across the genetic ancestry continuum
Polygenic scoring accuracy varies across the genetic ancestry continuum
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Polygenic scores (PGSs) have limited portability across different groupings of individuals (for example, by genetic ancestries and/or social determinants of health), preventing their equitable use
1
–
3
. PGS portability has typically been assessed using a single aggregate population-level statistic (for example,
R
2
)
4
...
Alternative Titles
Full title
Polygenic scoring accuracy varies across the genetic ancestry continuum
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10284707
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10284707
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06079-4
