STAT3-Mediated Promoter-Enhancer Interaction Up-Regulates Inhibitor of DNA Binding 1 (ID1) to Promot...
STAT3-Mediated Promoter-Enhancer Interaction Up-Regulates Inhibitor of DNA Binding 1 (ID1) to Promote Colon Cancer Progression
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Author / Creator
Lin, Zhike , Liu, Ying , Xu, Tian , Su, Ting , Yang, Yingying , Liang, Runhua , Gu, Songgang , Li, Jie , Song, Xuhong , Liang, Bin , Leng, Zhijun , Li, Yangsihan , Meng, Lele , Luo, Yijing , Chang, Xiaolan , Huang, Dongyang and Xie, Lingzhu
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Background: High expression of inhibitor of DNA binding 1 (ID1) correlates with poor prognosis in colorectal cancer (CRC). Aberrant enhancer activation in regulating ID1 transcription is limited. Methods: Immunohistochemistry (IHC), quantitative RT-PCR (RT-qPCR) and Western blotting (WB) were used to determine the expression of ID1. CRISPR-Cas9 was...
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Full title
STAT3-Mediated Promoter-Enhancer Interaction Up-Regulates Inhibitor of DNA Binding 1 (ID1) to Promote Colon Cancer Progression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10298663
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10298663
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms241210041