Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
About this item
Full title
Author / Creator
Mendiola, Andrew S. , Yan, Zhaoqi , Dixit, Karuna , Johnson, Jeffrey R. , Bouhaddou, Mehdi , Meyer-Franke, Anke , Shin, Min-Gyoung , Yong, Yu , Agrawal, Ayushi , MacDonald, Eilidh , Muthukumar, Gayathri , Pearce, Clairice , Arun, Nikhita , Cabriga, Belinda , Meza-Acevedo, Rosa , Alzamora, Maria del Pilar S. , Zamvil, Scott S. , Pico, Alexander R. , Ryu, Jae Kyu , Krogan, Nevan J. and Akassoglou, Katerina
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Blood protein extravasation through a disrupted blood–brain barrier and innate immune activation are hallmarks of neurological diseases and emerging therapeutic targets. However, how blood proteins polarize innate immune cells remains largely unknown. Here, we established an unbiased blood-innate immunity multiomic and genetic loss-of-function pipe...
Alternative Titles
Full title
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Authors, Artists and Contributors
Author / Creator
Yan, Zhaoqi
Dixit, Karuna
Johnson, Jeffrey R.
Bouhaddou, Mehdi
Meyer-Franke, Anke
Shin, Min-Gyoung
Yong, Yu
Agrawal, Ayushi
MacDonald, Eilidh
Muthukumar, Gayathri
Pearce, Clairice
Arun, Nikhita
Cabriga, Belinda
Meza-Acevedo, Rosa
Alzamora, Maria del Pilar S.
Zamvil, Scott S.
Pico, Alexander R.
Ryu, Jae Kyu
Krogan, Nevan J.
Akassoglou, Katerina
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10307624
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10307624
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-023-01522-0
