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Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10310813

Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

About this item

Full title

Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2023-06, Vol.14 (6), p.387-387, Article 387

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Wolfram syndrome (WS) is a rare neurodegenerative disorder encompassing diabetes
mellitus
, diabetes
insipidus
, optic atrophy, hearing loss (HL) as well as neurological disorders. None of the animal models of the pathology are presenting with an early onset HL, impeding the understanding of the role of Wolframin (WFS1), the protein res...

Alternative Titles

Full title

Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10310813

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10310813

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-023-05912-y

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