Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production
Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Wolfram syndrome (WS) is a rare neurodegenerative disorder encompassing diabetes
mellitus
, diabetes
insipidus
, optic atrophy, hearing loss (HL) as well as neurological disorders. None of the animal models of the pathology are presenting with an early onset HL, impeding the understanding of the role of Wolframin (WFS1), the protein res...
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Full title
Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10310813
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10310813
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-05912-y