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Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13

Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10312659

Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13

About this item

Full title

Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2023-03, Vol.30 (3), p.296-308

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The mycolic acid layer of the
Mycobacterium tuberculosis
cell wall is essential for viability and virulence, and the enzymes responsible for its synthesis are targets for antimycobacterial drug development. Polyketide synthase 13 (Pks13) is a module encoding several enzymatic and transport functions that carries out the condensation of two di...

Alternative Titles

Full title

Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10312659

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10312659

Other Identifiers

ISSN

1545-9993,1545-9985

E-ISSN

1545-9985

DOI

10.1038/s41594-022-00918-0

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