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Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10317898

Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

About this item

Full title

Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Diabetologia, 2023-08, Vol.66 (8), p.1501-1515

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aims/hypothesis
After birth, the neonatal islets gradually acquire glucose-responsive insulin secretion, a process that is subjected to maternal imprinting. Although NEFA are major components of breastmilk and insulin secretagogues, their role for functional maturation of neonatal beta cells is still unclear. NEFA are the endogenous ligands of f...

Alternative Titles

Full title

Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10317898

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10317898

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-023-05932-5

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