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Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expressio...

Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expressio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10329075

Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes

About this item

Full title

Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2023-08, Vol.146 (2), p.227-244

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Parkinson´s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Aggravation of symptoms is mirrored by accumulation of protein aggregates mainly composed by alpha-synuclein in different brain regions, called Lewy bodies (LB). Previous studies have identified several molecular mechanisms as au...

Alternative Titles

Full title

Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10329075

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10329075

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-023-02597-7

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