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A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10344783

A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

About this item

Full title

A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2023-07, Vol.41 (7), p.1004-1017

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Multiplexed fluorescence in situ hybridization (FISH) is a widely used approach for analyzing three-dimensional genome organization, but it is challenging to derive chromosomal conformations from noisy fluorescence signals, and tracing chromatin is not straightforward. Here we report a spatial genome aligner that parses true chromatin signal from n...

Alternative Titles

Full title

A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10344783

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10344783

Other Identifiers

ISSN

1087-0156,1546-1696

E-ISSN

1546-1696

DOI

10.1038/s41587-022-01568-9

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