A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH
A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Multiplexed fluorescence in situ hybridization (FISH) is a widely used approach for analyzing three-dimensional genome organization, but it is challenging to derive chromosomal conformations from noisy fluorescence signals, and tracing chromatin is not straightforward. Here we report a spatial genome aligner that parses true chromatin signal from n...
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Full title
A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10344783
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10344783
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ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01568-9