Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
About this item
Full title
Author / Creator
Anderson, Nathaniel D. , Birch, Jack , Accogli, Theo , Criado, Ignacio , Khabirova, Eleonora , Parks, Conor , Wood, Yvette , Young, Matthew D. , Porter, Tarryn , Richardson, Rachel , Albon, Sarah J. , Popova, Bilyana , Lopes, Andre , Wynn, Robert , Hough, Rachael , Gohil, Satyen H. , Pule, Martin , Amrolia, Persis J. , Behjati, Sam and Ghorashian, Sara
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
In the context of relapsed and refractory childhood pre-B cell acute lymphoblastic leukemia (R/R B-ALL), CD19-targeting chimeric antigen receptor (CAR)-T cells often induce durable remissions, which requires the persistence of CAR-T cells. In this study, we systematically analyzed CD19 CAR-T cells of 10 children with R/R B-ALL enrolled in the CARPA...
Alternative Titles
Full title
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
Authors, Artists and Contributors
Author / Creator
Birch, Jack
Accogli, Theo
Criado, Ignacio
Khabirova, Eleonora
Parks, Conor
Wood, Yvette
Young, Matthew D.
Porter, Tarryn
Richardson, Rachel
Albon, Sarah J.
Popova, Bilyana
Lopes, Andre
Wynn, Robert
Hough, Rachael
Gohil, Satyen H.
Pule, Martin
Amrolia, Persis J.
Behjati, Sam
Ghorashian, Sara
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10353931
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10353931
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-023-02415-3
