Investigation of targets and anticancer mechanisms of covalently acting natural products by function...
Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics
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Author / Creator
Zhao, Wen-si , Chen, Kai-feng , Liu, Man , Jia, Xing-long , Huang, Yu-qi , Hao, Bing-bing , Hu, Hao , Shen, Xiao-yan , Yu, Qiang and Tan, Min-jia
Publisher
Singapore: Springer Nature Singapore
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Language
English
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Publisher
Singapore: Springer Nature Singapore
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Contents
Eriocalyxin B (EB), 17-hydroxy-jolkinolide B (HJB), parthenolide (PN), xanthatin (XT) and andrographolide (AG) are terpenoid natural products with a variety of promising antitumor activities, which commonly bear electrophilic groups (α,β–unsaturated carbonyl groups and/or epoxides) capable of covalently modifying protein cysteine residues. However,...
Alternative Titles
Full title
Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374574
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374574
Other Identifiers
ISSN
1671-4083,1745-7254
E-ISSN
1745-7254
DOI
10.1038/s41401-023-01072-z