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Investigation of targets and anticancer mechanisms of covalently acting natural products by function...

Investigation of targets and anticancer mechanisms of covalently acting natural products by function...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374574

Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics

About this item

Full title

Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics

Publisher

Singapore: Springer Nature Singapore

Journal title

Acta pharmacologica Sinica, 2023-08, Vol.44 (8), p.1701-1711

Language

English

Formats

Publication information

Publisher

Singapore: Springer Nature Singapore

More information

Scope and Contents

Contents

Eriocalyxin B (EB), 17-hydroxy-jolkinolide B (HJB), parthenolide (PN), xanthatin (XT) and andrographolide (AG) are terpenoid natural products with a variety of promising antitumor activities, which commonly bear electrophilic groups (α,β–unsaturated carbonyl groups and/or epoxides) capable of covalently modifying protein cysteine residues. However,...

Alternative Titles

Full title

Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374574

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374574

Other Identifiers

ISSN

1671-4083,1745-7254

E-ISSN

1745-7254

DOI

10.1038/s41401-023-01072-z

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