The HDAC inhibitor domatinostat induces type I interferon α in Merkel cell carcinoma by HES1 repress...
The HDAC inhibitor domatinostat induces type I interferon α in Merkel cell carcinoma by HES1 repression
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Background
Class I selective histone deacetylase inhibitors (HDACi) have been previously demonstrated to not only increase major histocompatibility complex class I surface expression in Merkel cell carcinoma (MCC) cells by restoring the antigen processing and presentation machinery, but also exert anti-tumoral effect by inducing apoptosis. Both...
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Full title
The HDAC inhibitor domatinostat induces type I interferon α in Merkel cell carcinoma by HES1 repression
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374800
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10374800
Other Identifiers
ISSN
0171-5216,1432-1335
E-ISSN
1432-1335
DOI
10.1007/s00432-023-04733-y