Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and...
Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates
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Author / Creator
Zyk, Nikolai Y. , Garanina, Anastasiia S. , Plotnikova, Ekaterina A. , Ber, Anton P. , Nimenko, Ekaterina A. , Dashkova, Natalia S. , Uspenskaia, Anastasiia A. , Shafikov, Radik R. , Skvortsov, Dmitry A. , Petrov, Stanislav A. , Pankratov, Andrey A. , Zyk, Nikolai V. , Majouga, Alexander G. , Beloglazkina, Elena K. and Machulkin, Aleksei E.
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Prostate cancer is the second most common cancer among men. We designed and synthesized new ligands targeting prostate-specific membrane antigen and suitable for bimodal conjugates with diagnostic and therapeutic agents. In vitro studies of the affinity of the synthesized compounds to the protein target have been carried out. Based on these ligands...
Alternative Titles
Full title
Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates
Authors, Artists and Contributors
Author / Creator
Garanina, Anastasiia S.
Plotnikova, Ekaterina A.
Ber, Anton P.
Nimenko, Ekaterina A.
Dashkova, Natalia S.
Uspenskaia, Anastasiia A.
Shafikov, Radik R.
Skvortsov, Dmitry A.
Petrov, Stanislav A.
Pankratov, Andrey A.
Zyk, Nikolai V.
Majouga, Alexander G.
Beloglazkina, Elena K.
Machulkin, Aleksei E.
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10380083
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10380083
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms241411327