Synapse-tuned CARs enhance immune cell anti-tumor activity
Synapse-tuned CARs enhance immune cell anti-tumor activity
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Chimeric antigen receptor (CAR) technologies have been clinically implemented for the treatment of hematological malignancies; however, solid tumors remain resilient to CAR therapeutics. Natural killer (NK) cells may provide an optimal class of immune cells for CAR-based approaches due to their inherent anti-tumor functionality. In this study, we s...
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Synapse-tuned CARs enhance immune cell anti-tumor activity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10394118
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10394118
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ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01650-2