Log in to save to my catalogue

Synapse-tuned CARs enhance immune cell anti-tumor activity

Synapse-tuned CARs enhance immune cell anti-tumor activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10394118

Synapse-tuned CARs enhance immune cell anti-tumor activity

About this item

Full title

Synapse-tuned CARs enhance immune cell anti-tumor activity

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2023-10, Vol.41 (10), p.1434-1445

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Chimeric antigen receptor (CAR) technologies have been clinically implemented for the treatment of hematological malignancies; however, solid tumors remain resilient to CAR therapeutics. Natural killer (NK) cells may provide an optimal class of immune cells for CAR-based approaches due to their inherent anti-tumor functionality. In this study, we s...

Alternative Titles

Full title

Synapse-tuned CARs enhance immune cell anti-tumor activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10394118

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10394118

Other Identifiers

ISSN

1087-0156,1546-1696

E-ISSN

1546-1696

DOI

10.1038/s41587-022-01650-2

How to access this item