Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models...
Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models of neurodevelopmental disorders
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Astrocytes negatively impact neuronal development in many models of neurodevelopmental disorders (NDs); however, how they do this, and if mechanisms are shared across disorders, is not known. In this study, we developed a cell culture system to ask how astrocyte protein secretion and gene expression change in three mouse models of genetic NDs (Rett...
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Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models of neurodevelopmental disorders
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10395413
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10395413
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-022-01150-1