Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer
Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer
About this item
Full title
Author / Creator
Bruhm, Daniel C. , Mathios, Dimitrios , Foda, Zachariah H. , Annapragada, Akshaya V. , Medina, Jamie E. , Adleff, Vilmos , Chiao, Elaine Jiayuee , Ferreira, Leonardo , Cristiano, Stephen , White, James R. , Mazzilli, Sarah A. , Billatos, Ehab , Spira, Avrum , Zaidi, Ali H. , Mueller, Jeffrey , Kim, Amy K. , Anagnostou, Valsamo , Phallen, Jillian , Scharpf, Robert B. and Velculescu, Victor E.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive diagnosis of cancer. We analyzed whole-genome sequencing data from 2,511 individuals in the Pan-Cancer Analysis of Whole Genomes (PCAWG) study as well as 489 individuals from four prospective cohorts and found distinct regional mutation type-specific frequencies in...
Alternative Titles
Full title
Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer
Authors, Artists and Contributors
Author / Creator
Mathios, Dimitrios
Foda, Zachariah H.
Annapragada, Akshaya V.
Medina, Jamie E.
Adleff, Vilmos
Chiao, Elaine Jiayuee
Ferreira, Leonardo
Cristiano, Stephen
White, James R.
Mazzilli, Sarah A.
Billatos, Ehab
Spira, Avrum
Zaidi, Ali H.
Mueller, Jeffrey
Kim, Amy K.
Anagnostou, Valsamo
Phallen, Jillian
Scharpf, Robert B.
Velculescu, Victor E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10412448
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10412448
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-023-01446-3
