Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotr...
Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Engineered live bacteria could provide a new modality for treating lung infections, a major cause of mortality worldwide. In the present study, we engineered a genome-reduced human lung bacterium,
Mycoplasma pneumoniae
, to treat ventilator-associated pneumonia, a disease with high hospital mortality when associated with
Pseudomonas aerugi...
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Full title
Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10421741
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10421741
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01584-9
