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Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage....

Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage....

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10425486

Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial

About this item

Full title

Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Intensive care medicine, 2023-08, Vol.49 (8), p.922-933

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
This study aimed at determining whether intravenous artesunate is safe and effective in reducing multiple organ dysfunction syndrome in trauma patients with major hemorrhage.
Methods
TOP-ART, a randomized, blinded, placebo-controlled, phase IIa trial, was conducted at a London major trauma center in adult trauma patients who activa...

Alternative Titles

Full title

Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10425486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10425486

Other Identifiers

ISSN

0342-4642

E-ISSN

1432-1238

DOI

10.1007/s00134-023-07135-3

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