Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY...
Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial
About this item
Full title
Author / Creator
Mosele, Fernanda , Deluche, Elise , Lusque, Amelie , Le Bescond, Loïc , Filleron, Thomas , Pradat, Yoann , Ducoulombier, Agnes , Pistilli, Barbara , Bachelot, Thomas , Viret, Frederic , Levy, Christelle , Signolle, Nicolas , Alfaro, Alexia , Tran, Diep T. N. , Garberis, Ingrid Judith , Talbot, Hugues , Christodoulidis, Stergios , Vakalopoulou, Maria , Droin, Nathalie , Stourm, Aurelie , Kobayashi, Maki , Kakegawa, Tomoya , Lacroix, Ludovic , Saulnier, Patrick , Job, Bastien , Deloger, Marc , Jimenez, Marta , Mahier, Celine , Baris, Vianney , Laplante, Pierre , Kannouche, Patricia , Marty, Virginie , Lacroix-Triki, Magali , Diéras, Veronique and André, Fabrice
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The mechanisms of action of and resistance to trastuzumab deruxtecan (T-DXd), an anti-HER2–drug conjugate for breast cancer treatment, remain unclear. The phase 2 DAISY trial evaluated the efficacy of T-DXd in patients with HER2-overexpressing (
n
= 72, cohort 1), HER2-low (
n
= 74, cohort 2) and HER2 non-expressing (
n
= 40, c...
Alternative Titles
Full title
Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial
Authors, Artists and Contributors
Author / Creator
Deluche, Elise
Lusque, Amelie
Le Bescond, Loïc
Filleron, Thomas
Pradat, Yoann
Ducoulombier, Agnes
Pistilli, Barbara
Bachelot, Thomas
Viret, Frederic
Levy, Christelle
Signolle, Nicolas
Alfaro, Alexia
Tran, Diep T. N.
Garberis, Ingrid Judith
Talbot, Hugues
Christodoulidis, Stergios
Vakalopoulou, Maria
Droin, Nathalie
Stourm, Aurelie
Kobayashi, Maki
Kakegawa, Tomoya
Lacroix, Ludovic
Saulnier, Patrick
Job, Bastien
Deloger, Marc
Jimenez, Marta
Mahier, Celine
Baris, Vianney
Laplante, Pierre
Kannouche, Patricia
Marty, Virginie
Lacroix-Triki, Magali
Diéras, Veronique
André, Fabrice
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10427426
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10427426
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X,1744-7933
DOI
10.1038/s41591-023-02478-2
