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Transient naive reprogramming corrects hiPS cells functionally and epigenetically

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10447250

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

About this item

Full title

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-08, Vol.620 (7975), p.863-872

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cells undergo a major epigenome reconfiguration when reprogrammed to human induced pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human embryonic stem (hES) cells differ significantly, which affects hiPS cell function
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8
. These differences include epigenetic memory and aberrations that emerge during r...

Alternative Titles

Full title

Transient naive reprogramming corrects hiPS cells functionally and epigenetically

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10447250

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10447250

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06424-7

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