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Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeuti...

Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeuti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10462669

Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate

About this item

Full title

Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate

Publisher

Singapore: Springer Nature Singapore

Journal title

Acta pharmacologica Sinica, 2023-09, Vol.44 (9), p.1801-1814

Language

English

Formats

Publication information

Publisher

Singapore: Springer Nature Singapore

More information

Scope and Contents

Contents

Liver, as an immune and detoxification organ, represents an important line of defense against bacteria and infection and a vulnerable organ that is easily injured during sepsis. Artesunate (ART) is an anti-malaria agent, that also exhibits broad pharmacological activities including anti-inflammatory, immune-regulation and liver protection. In this...

Alternative Titles

Full title

Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10462669

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10462669

Other Identifiers

ISSN

1671-4083,1745-7254

E-ISSN

1745-7254

DOI

10.1038/s41401-023-01065-y

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