Elamipretide reduces pyroptosis and improves functional recovery after spinal cord injury
Elamipretide reduces pyroptosis and improves functional recovery after spinal cord injury
About this item
Full title
Author / Creator
Jiang, Wu , He, Fan , Ding, Guoming and Wu, Junsong
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Elamipretide (EPT), a novel mitochondria-targeted peptide, has been shown to be protective in a range of diseases. However, the effect of EPT in spinal cord injury (SCI) has yet to be elucidated. We aimed to investigate whether EPT would inhibit pyroptosis and protect against SCI.
After establishing the SCI model, we determined the biochemical a...
Alternative Titles
Full title
Elamipretide reduces pyroptosis and improves functional recovery after spinal cord injury
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10493668
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10493668
Other Identifiers
ISSN
1755-5930
E-ISSN
1755-5949
DOI
10.1111/cns.14221
