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Lipid saturation controls nuclear envelope function

Lipid saturation controls nuclear envelope function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10495262

Lipid saturation controls nuclear envelope function

About this item

Full title

Lipid saturation controls nuclear envelope function

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2023-09, Vol.25 (9), p.1290-1302

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The nuclear envelope (NE) is a spherical double membrane with elastic properties. How NE shape and elasticity are regulated by lipid chemistry is unknown. Here we discover lipid acyl chain unsaturation as essential for NE and nuclear pore complex (NPC) architecture and function. Increased lipid saturation rigidifies the NE and the endoplasmic retic...

Alternative Titles

Full title

Lipid saturation controls nuclear envelope function

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10495262

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10495262

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-023-01207-8

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