A lentiviral vector for the production of T cells with an inducible transgene and a constitutively e...
A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Vectors that facilitate the engineering of T cells that can better harness endogenous immunity and overcome suppressive barriers in the tumour microenvironment would help improve the safety and efficacy of T-cell therapies for more patients. Here we report the design, production and applicability, in T-cell engineering, of a lentiviral vector lever...
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Full title
A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10504085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10504085
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ISSN
2157-846X
E-ISSN
2157-846X
DOI
10.1038/s41551-023-01013-5
