Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain
Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain
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England: Nature Publishing Group
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English
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England: Nature Publishing Group
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Tricyclic antidepressants (TCAs), such as desipramine (DMI), are effective at managing neuropathic pain symptoms but often take several weeks to become effective and also lead to considerable side effects. Tianeptine (TIAN) is an atypical antidepressant that activates the mu-opioid receptor but does not produce analgesic tolerance or withdrawal in...
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Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10517169
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10517169
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0893-133X,1740-634X
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1740-634X
DOI
10.1038/s41386-023-01645-w