Tyrosine Kinase Inhibitor Profiling Using Multiple Forskolin-Responsive Reporter Cells
Tyrosine Kinase Inhibitor Profiling Using Multiple Forskolin-Responsive Reporter Cells
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
We have developed a highly sensitive promoter trap vector system using transposons to generate reporter cells with high efficiency. Using an EGFP/luciferase reporter cell clone responsive to forskolin, which is thought to activate adenylate cyclase, isolated from human chronic myelogenous leukemia cell line K562, we found several compounds unexpect...
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Full title
Tyrosine Kinase Inhibitor Profiling Using Multiple Forskolin-Responsive Reporter Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10530646
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10530646
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms241813863
