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Unsupervised [18F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease

Unsupervised [18F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10542510

Unsupervised [18F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease

About this item

Full title

Unsupervised [18F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European journal of nuclear medicine and molecular imaging, 2023-09, Vol.50 (11), p.3265-3275

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Several [
18
F]Flortaucipir cutoffs have been proposed for tau PET positivity (T
+
) in Alzheimer’s disease (AD), but none were data-driven. The aim of this study was to establish and validate unsupervised T
+
cutoffs by applying Gaussian mixture models (GMM).
Methods
Amyloid negative (A

) cognitively norm...

Alternative Titles

Full title

Unsupervised [18F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10542510

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10542510

Other Identifiers

ISSN

1619-7070

E-ISSN

1619-7089

DOI

10.1007/s00259-023-06280-7

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