A novel small-molecular CCR5 antagonist promotes neural repair after stroke
A novel small-molecular CCR5 antagonist promotes neural repair after stroke
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Publisher
Singapore: Springer Nature Singapore
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Language
English
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Publisher
Singapore: Springer Nature Singapore
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Chemokine receptor 5 (CCR5) is one of the main co-receptors of HIV-1, and has been found to be a potential therapeutic target for stroke. Maraviroc is a classic CCR5 antagonist, which is undergoing clinical trials against stroke. As maraviroc shows poor blood-brain barrier (BBB) permeability, it is of interest to find novel CCR5 antagonists suitabl...
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Full title
A novel small-molecular CCR5 antagonist promotes neural repair after stroke
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10545720
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10545720
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ISSN
1671-4083,1745-7254
E-ISSN
1745-7254
DOI
10.1038/s41401-023-01100-y
