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Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentia...

Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10567550

Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation

About this item

Full title

Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2023-10, Vol.25 (10), p.1426-1438

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dedifferentiation is the process by which terminally differentiated cells acquire the properties of stem cells. During mouse skin wound healing, the differentiated Gata6-lineage positive cells of the sebaceous duct are able to dedifferentiate. Here we have integrated lineage tracing and single-cell mRNA sequencing to uncover the underlying mechanis...

Alternative Titles

Full title

Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10567550

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10567550

Other Identifiers

ISSN

1465-7392,1476-4679

E-ISSN

1476-4679

DOI

10.1038/s41556-023-01234-5

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