Peripheral temperature dysregulation associated with functionally altered NaV1.8 channels
Peripheral temperature dysregulation associated with functionally altered NaV1.8 channels
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
The voltage-gated sodium channel Na
V
1.8 is prominently expressed in the soma and axons of small-caliber sensory neurons, and pathogenic variants of the corresponding gene
SCN10A
are associated with peripheral pain and autonomic dysfunction. While most disease-associated
SCN10A
variants confer gain-of-function properties to Na
Alternative Titles
Full title
Peripheral temperature dysregulation associated with functionally altered NaV1.8 channels
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10567936
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10567936
Other Identifiers
ISSN
0031-6768
E-ISSN
1432-2013
DOI
10.1007/s00424-023-02856-2