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Selective Activation of M1 Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation

Selective Activation of M1 Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10571583

Selective Activation of M1 Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation

About this item

Full title

Selective Activation of M1 Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation

Publisher

Basel: MDPI AG

Journal title

Cancers, 2023-09, Vol.15 (19), p.4766

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

M3 muscarinic receptor (M3R) activation stimulates colon cancer cell proliferation, migration, and invasion; M3R expression is augmented in colon cancer and ablating M3R expression in mice attenuates colon neoplasia. Several lines of investigation suggest that in contrast to these pro-neoplastic effects of M3R, M1R plays an opposite role, protectin...

Alternative Titles

Full title

Selective Activation of M1 Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10571583

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10571583

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers15194766

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