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Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy

Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10574198

Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy

About this item

Full title

Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy

Publisher

Switzerland: MDPI AG

Journal title

Nutrients, 2023-09, Vol.15 (19), p.4127

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The pathophysiology of chronic kidney disease-mineral and bone disorder (CKD-MBD) is not well understood. Specific factors secreted by osteocytes are elevated in the serum of adults and pediatric patients with CKD-MBD, including FGF-23 and sclerostin, a known inhibitor of the Wnt signaling pathway. The molecular mechanisms that promote bone disease...

Alternative Titles

Full title

Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10574198

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10574198

Other Identifiers

ISSN

2072-6643

E-ISSN

2072-6643

DOI

10.3390/nu15194127

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