Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy
Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The pathophysiology of chronic kidney disease-mineral and bone disorder (CKD-MBD) is not well understood. Specific factors secreted by osteocytes are elevated in the serum of adults and pediatric patients with CKD-MBD, including FGF-23 and sclerostin, a known inhibitor of the Wnt signaling pathway. The molecular mechanisms that promote bone disease...
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Full title
Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10574198
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10574198
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ISSN
2072-6643
E-ISSN
2072-6643
DOI
10.3390/nu15194127