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Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human pri...

Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human pri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10575780

Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Crossing the blood–brain barrier in primates is a major obstacle for gene delivery to the brain. Adeno-associated viruses (AAVs) promise robust, non-invasive gene delivery from the bloodstream to the brain. However, unlike in rodents, few neurotropic AAVs efficiently cross the blood–brain barrier in non-human primates. Here we report on AAV.CAP-Mac...

Alternative Titles

Full title

Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10575780

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10575780

Other Identifiers

ISSN

1748-3387

E-ISSN

1748-3395

DOI

10.1038/s41565-023-01419-x

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