Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell r...
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn’s disease
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Author / Creator
Martini, Gabriela Rios , Tikhonova, Ekaterina , Rosati, Elisa , DeCelie, Meghan Bialt , Sievers, Laura Katharina , Tran, Florian , Lessing, Matthias , Bergfeld, Arne , Hinz, Sophia , Nikolaus, Susanna , Kümpers, Julia , Matysiak, Anna , Hofmann, Philipp , Saggau, Carina , Schneiders, Stephan , Kamps, Ann-Kristin , Jacobs, Gunnar , Lieb, Wolfgang , Maul, Jochen , Siegmund, Britta , Seegers, Barbara , Hinrichsen, Holger , Oberg, Hans-Heinrich , Wesch, Daniela , Bereswill, Stefan , Heimesaat, Markus M. , Rupp, Jan , Kniemeyer, Olaf , Brakhage, Axel A. , Brunke, Sascha , Hube, Bernhard , Aden, Konrad , Franke, Andre , Iliev, Iliyan D. , Scheffold, Alexander , Schreiber, Stefan and Bacher, Petra
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
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Contents
Aberrant CD4
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T cell reactivity against intestinal microorganisms is considered to drive mucosal inflammation in inflammatory bowel diseases. The disease-relevant microbial species and the corresponding microorganism-specific, pathogenic T cell phenotypes remain largely unknown. In the present study, we identified common gut commensal and fo...
Alternative Titles
Full title
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn’s disease
Authors, Artists and Contributors
Author / Creator
Tikhonova, Ekaterina
Rosati, Elisa
DeCelie, Meghan Bialt
Sievers, Laura Katharina
Tran, Florian
Lessing, Matthias
Bergfeld, Arne
Hinz, Sophia
Nikolaus, Susanna
Kümpers, Julia
Matysiak, Anna
Hofmann, Philipp
Saggau, Carina
Schneiders, Stephan
Kamps, Ann-Kristin
Jacobs, Gunnar
Lieb, Wolfgang
Maul, Jochen
Siegmund, Britta
Seegers, Barbara
Hinrichsen, Holger
Oberg, Hans-Heinrich
Wesch, Daniela
Bereswill, Stefan
Heimesaat, Markus M.
Rupp, Jan
Kniemeyer, Olaf
Brakhage, Axel A.
Brunke, Sascha
Hube, Bernhard
Aden, Konrad
Franke, Andre
Iliev, Iliyan D.
Scheffold, Alexander
Schreiber, Stefan
Bacher, Petra
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10579100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10579100
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-023-02556-5
