PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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The conserved multiple PDZ-domain containing protein PATJ stabilizes the Crumbs-Pals1 complex to regulate apical-basal polarity and tight junction formation in epithelial cells. However, the molecular mechanism of PATJ’s function in these processes is still unclear. In this study, we demonstrate that knockout of PATJ in epithelial cells results in...
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Full title
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10600057
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10600057
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ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-023-04994-3