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PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity

PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10600057

PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity

About this item

Full title

PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2023-11, Vol.80 (11), p.333-333, Article 333

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

The conserved multiple PDZ-domain containing protein PATJ stabilizes the Crumbs-Pals1 complex to regulate apical-basal polarity and tight junction formation in epithelial cells. However, the molecular mechanism of PATJ’s function in these processes is still unclear. In this study, we demonstrate that knockout of PATJ in epithelial cells results in...

Alternative Titles

Full title

PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10600057

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10600057

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-023-04994-3

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