Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and base...
Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Age, female sex, and apolipoprotein E4 (E4) are risk factors to develop Alzheimer’s disease (AD). There are three major human apoE isoforms: E2, E3, and E4. Compared to E3, E4 increases while E2 decreases AD risk. However, E2 is associated with increased risk and severity of post-traumatic stress disorder (PTSD). In cognitively healthy adults, E4 c...
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Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10618101
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10618101
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1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-023-01966-8
