Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a...
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
About this item
Full title
Author / Creator
Yin, Zhuoran , Herron, Shawn , Silveira, Sebastian , Kleemann, Kilian , Gauthier, Christian , Mallah, Dania , Cheng, Yiran , Margeta, Milica A. , Pitts, Kristen M. , Barry, Jen-Li , Subramanian, Ayshwarya , Shorey, Hannah , Brandao, Wesley , Durao, Ana , Delpech, Jean-Christophe , Madore, Charlotte , Jedrychowski, Mark , Ajay, Amrendra K. , Murugaiyan, Gopal , Hersh, Samuel W. , Ikezu, Seiko , Ikezu, Tsuneya and Butovsky, Oleg
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Microglia play a critical role in brain homeostasis and disease progression. In neurodegenerative conditions, microglia acquire the neurodegenerative phenotype (MGnD), whose function is poorly understood. MicroRNA-155 (miR-155), enriched in immune cells, critically regulates MGnD. However, its role in Alzheimer’s disease (AD) pathogenesis remains u...
Alternative Titles
Full title
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Herron, Shawn
Silveira, Sebastian
Kleemann, Kilian
Gauthier, Christian
Mallah, Dania
Cheng, Yiran
Margeta, Milica A.
Pitts, Kristen M.
Barry, Jen-Li
Subramanian, Ayshwarya
Shorey, Hannah
Brandao, Wesley
Durao, Ana
Delpech, Jean-Christophe
Madore, Charlotte
Jedrychowski, Mark
Ajay, Amrendra K.
Murugaiyan, Gopal
Hersh, Samuel W.
Ikezu, Seiko
Ikezu, Tsuneya
Butovsky, Oleg
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10619638
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10619638
Other Identifiers
ISSN
1097-6256,1546-1726
E-ISSN
1546-1726
DOI
10.1038/s41593-023-01355-y
