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Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10628994

Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Even among genetically identical cancer cells, resistance to therapy frequently emerges from a small subset of those cells
1

7
. Molecular differences in rare individual cells in the initial population enable certain cells to become resistant to therapy
7

9
; however, comparatively little is known about the variability i...

Alternative Titles

Full title

Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10628994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10628994

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06342-8

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