Pangenome graph construction from genome alignments with Minigraph-Cactus
Pangenome graph construction from genome alignments with Minigraph-Cactus
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Pangenome references address biases of reference genomes by storing a representative set of diverse haplotypes and their alignment, usually as a graph. Alternate alleles determined by variant callers can be used to construct pangenome graphs, but advances in long-read sequencing are leading to widely available, high-quality phased assemblies. Const...
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Full title
Pangenome graph construction from genome alignments with Minigraph-Cactus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10638906
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10638906
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-023-01793-w