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Synthesis of portimines reveals the basis of their anti-cancer activity

Synthesis of portimines reveals the basis of their anti-cancer activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10699793

Synthesis of portimines reveals the basis of their anti-cancer activity

About this item

Full title

Synthesis of portimines reveals the basis of their anti-cancer activity

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-10, Vol.622 (7983), p.507-513

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Marine-derived cyclic imine toxins, portimine A and portimine B, have attracted attention because of their chemical structure and notable anti-cancer therapeutic potential
1

4
. However, access to large quantities of these toxins is currently not feasible, and the molecular mechanism underlying their potent activity remains unknown un...

Alternative Titles

Full title

Synthesis of portimines reveals the basis of their anti-cancer activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10699793

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10699793

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06535-1

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