An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh exp...
An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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United States: American Society for Clinical Investigation
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Contents
Short digits (Dsh) is a radiation-induced mouse mutant. Homozygous mice are characterized by multiple defects strongly resembling those resulting from Sonic hedgehog (Shh) inactivation. Heterozygous mice show a limb reduction phenotype with fusion and shortening of the proximal and middle phalanges in all digits, similar to human brachydactyly type...
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Full title
An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1070420
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1070420
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI200523675
