Aryl hydrocarbon receptor sulfenylation promotes glycogenolysis and rescues cancer chemoresistance
Aryl hydrocarbon receptor sulfenylation promotes glycogenolysis and rescues cancer chemoresistance
About this item
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Author / Creator
Zhou, Nannan , Chen, Jie , Ling, Zheng , Zhang, Chaoqi , Zhou, Yabo , Wang, Dianheng , Zhou, Li , Wang, Zhenfeng , Sun, Nan , Wang, Xin , Zhang, Huafeng , Tang, Ke , Ma, Jingwei , Lv, Jiadi and Huang, Bo
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Elevation of reactive oxygen species (ROS) levels is a general consequence of tumor cells' response to treatment and may cause tumor cell death. Mechanisms by which tumor cells clear fatal ROS, thereby rescuing redox balance and entering a chemoresistant state, remain unclear. Here, we show that cysteine sulfenylation by ROS confers on aryl hydroca...
Alternative Titles
Full title
Aryl hydrocarbon receptor sulfenylation promotes glycogenolysis and rescues cancer chemoresistance
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10721154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10721154
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI170753
