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Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications

Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10730688

Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications

About this item

Full title

Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Pflügers Archiv, 2023-12, Vol.475 (12), p.1387-1407

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Animal opsins are light activated G-protein-coupled receptors, capable of optogenetic control of G-protein signalling for research or therapeutic applications. Animal opsins offer excellent photosensitivity, but their temporal resolution can be limited by long photoresponse duration when expressed outside their native cellular environment. Here, we...

Alternative Titles

Full title

Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10730688

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10730688

Other Identifiers

ISSN

0031-6768

E-ISSN

1432-2013

DOI

10.1007/s00424-023-02879-9

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