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Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivat...

Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10760960

Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation

About this item

Full title

Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2024-01, Vol.134 (1), p.1-16

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The infertility of many couples rests on an enigmatic dysfunction of the man's sperm. To gain insight into the underlying pathomechanisms, we assessed the function of the sperm-specific multisubunit CatSper-channel complex in the sperm of almost 2,300 men undergoing a fertility workup, using a simple motility-based test. We identified a group of me...

Alternative Titles

Full title

Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10760960

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10760960

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI173564

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