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The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series...

The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10761519

The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series) using toxicology in silico methods

About this item

Full title

The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series) using toxicology in silico methods

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2024-01, Vol.98 (1), p.267-275

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Nerve agents are organophosphate chemical warfare agents that exert their toxic effects by irreversibly inhibiting acetylcholinesterase, affecting the breakdown of the neurotransmitter acetylcholine in the synaptic cleft. Due to the risk of exposure to dangerous nerve agents and for animal welfare reasons, in silico methods have been used to assess...

Alternative Titles

Full title

The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series) using toxicology in silico methods

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10761519

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10761519

Other Identifiers

ISSN

0340-5761,1432-0738

E-ISSN

1432-0738

DOI

10.1007/s00204-023-03632-y

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