The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series...
The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series) using toxicology in silico methods
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Nerve agents are organophosphate chemical warfare agents that exert their toxic effects by irreversibly inhibiting acetylcholinesterase, affecting the breakdown of the neurotransmitter acetylcholine in the synaptic cleft. Due to the risk of exposure to dangerous nerve agents and for animal welfare reasons, in silico methods have been used to assess...
Alternative Titles
Full title
The prediction of acute toxicity (LD50) for organophosphorus-based chemical warfare agents (V-series) using toxicology in silico methods
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Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10761519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10761519
Other Identifiers
ISSN
0340-5761,1432-0738
E-ISSN
1432-0738
DOI
10.1007/s00204-023-03632-y