Disease-specific tau filaments assemble via polymorphic intermediates
Disease-specific tau filaments assemble via polymorphic intermediates
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Intermediate species in the assembly of amyloid filaments are believed to play a central role in neurodegenerative diseases and may constitute important targets for therapeutic intervention
1
,
2
. However, structural information about intermediate species has been scarce and the molecular mechanisms by which amyloids assemble remain la...
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Full title
Disease-specific tau filaments assemble via polymorphic intermediates
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764278
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764278
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06788-w