Log in to save to my catalogue

Disease-specific tau filaments assemble via polymorphic intermediates

Disease-specific tau filaments assemble via polymorphic intermediates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764278

Disease-specific tau filaments assemble via polymorphic intermediates

About this item

Full title

Disease-specific tau filaments assemble via polymorphic intermediates

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2024-01, Vol.625 (7993), p.119-125

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Intermediate species in the assembly of amyloid filaments are believed to play a central role in neurodegenerative diseases and may constitute important targets for therapeutic intervention
1
,
2
. However, structural information about intermediate species has been scarce and the molecular mechanisms by which amyloids assemble remain la...

Alternative Titles

Full title

Disease-specific tau filaments assemble via polymorphic intermediates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764278

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10764278

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06788-w

How to access this item